How to make your own neti pot saline solution mix (for sinus cleansing). This recipe makes 60 doses, equivalent to a box of mixture you might purchase at the drugstore. I determined the proper ingredients, ratios, and dose size from saline solution mix sold over-the-counter. I only recommend using this recipe if you're familiar with how neti pots work. Non-iodized salt is the normal ingredient for neti pot solution - the additional baking soda (sodium bicarbonate) seems to help sooth nasal passages. If you're uncertain about the baking soda, omit it and just use the salt. Simple, yet effective.